In E17.5 Snrk KO hearts we noticed a decreasing trend in pACC, which was statistically significant in P0 neonates. pAMPKα a regulator of pACC ( Folmes and Lopaschuk, 2007 ) was also lower at E17.5 in Snrk KO hearts.
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Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolism.
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