Assessment of Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans in Down's syndrome subjects and systemically healthy subjects: A comparative clinical trial.

Elevated levels of Pg in DS subjects resulting in early onset periodontitis could be due to the more susceptible host for the causative microbial agents including Pg with type II Fimbrea.[ 19 ] In the present study both Pg and Aac were elevated in DS subjects with gingivitis and periodontitis compared to healthy controls, further there is a highly significant increase in the level of Pg than Aac in DS gingivitis group.

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