borderline significanceP = 0.06
Consistently, the tumor-bearing mice living in the EE conditions showed decreased trend of anxiety-like behaviors with borderline significance (time in open arm: SE = 50.1 ± 10.8 s, EE = 79.2 ± 10.3 s, P = 0.06; percentage of distance travelled in open arm: SE = 7.9 ± 1.3%, EE = 12.1 ± 1.7%, P = 0.07) ( Figure 1D ).