Mitochondrial protection by the mixed muscarinic/σ1 ligand ANAVEX2-73, a tetrahydrofuran derivative, in Aβ25-35 peptide-injected mice, a nontransgenic Alzheimer's disease model.

The IP pretreatment with ANAVEX2-73, in the 0.01–1 mg/kg dose-range dose-dependently prevented the Aβ 25–35 -induced increase in lipid peroxidation with highly significant effect measured at 0.3 and 1 mg/kg (Figure 1B ).

also in 132,142 other papers