The Chondrogenic Potential of Mesenchymal Cells and Chondrocytes from Osteoarthritic Subjects: A Comparative Analysis.

Analysis of the doubling time for chondrocytes isolated from either moderate or severely affected OA cartilage showed no significant difference between them, although both tissue types demonstrated a highly significant decrease in doubling time when the cells were cultured with FGF2v1 (2.5 days with ligand vs 5.8 days without ligand for the moderate and 2.5 vs 5.4 days for the severely affected OA chondrocytes; Table 1 ).

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