highly significantP < 0.0001
This was supported by statistical analysis that revealed that the frequency of polarization in HIV-1-infected T cells was highly significant compared to contacts formed between two uninfected T cells (odds ratio [OR] at 10 min, 1; OR at 20 min, 9; OR at 60 min, 17.9; Fisher's exact test, P < 0.0001) ( Fig. 1C ).