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Prevalence of hyperhomocysteinemia in China: a systematic review and meta-analysis.

Nutrients · 2014 · PMC4303827 · PMID 25551247

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a decreasing trendno p-value reported
Our previous studies found that the frequencies of 677T allele and 677 TT genotype showed a decreasing trend from northern to southern China [ 13 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.