Putting the pieces together: How is the mitochondrial pathway of apoptosis regulated in cancer and chemotherapy?

Cancer Metab · 2014 · PMC4304082 · PMID 25621172

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highly significantno p-value reported

These pharmacological agents are highly significant to designing precision treatments as tumors frequently display dependency upon BCL-2 or MCL-1, and chemo-resistant tumors often shift reliance between anti-apoptotic BCL-2 proteins.

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