A review of creatine supplementation in age-related diseases: more than a supplement for athletes.

F1000Res · 2014 · PMC4304302 · PMID 25664170

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an observed trendno p-value reported

Although there is an observed trend toward enhanced survival following creatine supplementation, these studies distinguished between large differences (30–50% difference).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.