As a consequence, the economic burden of GAD in current health systems has been evaluated as highly significant [ 7 , 8 ].
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Clinical and economic outcomes of adjunctive therapy with pregabalin or usual care in generalized anxiety disorder patients with partial response to selective serotonin reuptake inhibitors.
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The sentences
The overall significant increase in the drug costs in the pregabalin group of patients was compensated by significant reductions in the number of visits and almost significant in the number of hospitalizations in this group of patients.