Effect of cardiac resynchronization therapy with implantable cardioverter defibrillator versus cardiac resynchronization therapy with pacemaker on mortality in heart failure patients: results of a high-volume, single-centre experience.

There was a borderline significant difference in mortality reduction with CRT-D in patients with ischaemic cardiomyopathy compared with those with non-ischaemic cardiomyopathy (unadjusted interaction P -value = 0.099, adjusted interaction P -value = 0.153), suggestive of an incremental beneficial effect of CRT-D over CRT-P in ischaemic patients, but not in patients with non-ischaemic cardiomyopathy.

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