Testing for baseline differences in randomized controlled trials: an unhealthy research behavior that is hard to eradicate.

These reviews show a decreasing trend in the reporting of tests for baseline differences from it being an “ubiquitous error” in the 1978 and 79 issues of the NEJM [ 8 ] to 38.2% of the RCT’s published in the NEJM, the JAMA, the Lancet and the BMJ in the first half of 2007 [ 6 ].

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