Endogenous cholinergic neurotransmission contributes to behavioral sensitization to morphine.

PLoS One · 2015 · PMC4315441 · PMID 25647082

Europe PMC DOI

hedged sentences

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closest p · 1.0× alpha

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boldest claim

The sentences

marginally non-significantp = 0.05actually significant

Reported genes included genes exhibiting any expression change that was significant (p<0.05) or had more than 2-fold change (100%) but was statistically marginally non-significant (p = 0.05–0.2). 2.3.

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a trend toward significanceno p-value reported

Specifically, 2 genes were significantly different (upregulation of AChe and downregulation of Chrna3 ), while 2 other genes showed a large magnitude of difference, but only a trend toward significance (upregulation of Chat , and downregulation of Chrnb4 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.