Barely Significant
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Hormone replacement therapy and Parkinson's disease risk in women: a meta-analysis of 14 observational studies.

Neuropsychiatr Dis Treat · 2015 · PMC4317144 · PMID 25657580

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a nonsignificant trendno p-value reported
31 A more recent multicenter randomized, double-blind, placebo-controlled pilot trial from the Parkinson Study Group POETRY Investigators showed a nonsignificant trend of symptomatic and functional improvement in those receiving ERT. 32 Concerning the small number of participants included in each original study, it is conceivable that the conflicting results were due to the small sample size.

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