Cariprazine exerts antimanic properties and interferes with dopamine D2 receptor β-arrestin interactions.

Pharmacol Res Perspect · 2015 · PMC4317219 · PMID 25692006

Europe PMC DOI

hedged sentence

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

bordered on significanceP < 0.08so close (0.05 < p ≤ 0.1)

Treatment with 0.06 and 0.5 mg/kg cariprazine for 7 days, as well as 7 days of treatment with lithium, showed decreases in hyperactivity that bordered on significance (111.8 ± 22.94, 110.20 ± 19.18, and 130.1 ± 17.40, respectively; P < 0.08).

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