Expression of progerin in aging mouse brains reveals structural nuclear abnormalities without detectible significant alterations in gene expression, hippocampal stem cells or behavior.

Hum Mol Genet · 2015 · PMC4321440 · PMID 25343989

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possibly significantno p-value reported

Behavioral assays reveal no effect on memory in HGPS animals To functionally evaluate a possibly significant pathology in the hippocampi of the HGPS animals, we performed behavioral assays.

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an increasing trendno p-value reported

Relative expression levels of miR-23a showed an increasing trend with age.

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