Regulation of epithelial-mesenchymal transition in breast cancer cells by cell contact and adhesion.

50 With regard to the highly significant overlap ( P = 1.9E − 184) with the dataset comparing MDA-MB-231 cells vs MCF10A cells, it was striking that the majority of the 2385 overlapping gene features showed a negative correlation ( Fig. 2E ), indicating that more than 2/3 of the transcriptional alterations induced by low density cultivation of MCF10A cells overlapped significantly with MDA-MB-231 cells.

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