highly significantp-value < 0.05
The statistical significance of the difference between the two correlation coefficients, for a given time point, was calculated using a one-tailed Fisher test; highly significant differences between two correlation coefficients are indicated by a p-value < 0.05. qRT-PCR analysis Total RNA was extracted from one confluent well of a 6-well dish using the RNeasy Mini Kit with on-column DNAse digestion (Qiagen). cDNA was generated using the Superscript III First Strand Kit via the Oligo-dT method (Life Technologies). qRT-PCR was carried out using the Brilliant III SYBR QPCR Master Mix (Agilent Technologies) on a Lightcycler 480 (Roche).