As expected the majority of proteins cluster around the 1:1 ratio, corresponding to non-specific interactors, but there were also some notable proteins common to both tags which appeared as highly significant that lay > 1SD from the median ratio ( Supplemental Table S4 A , Table 4 in [23] ).
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SILAC-iPAC: a quantitative method for distinguishing genuine from non-specific components of protein complexes by parallel affinity capture.
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