Identifying the integrated neural networks involved in capsaicin-induced pain using fMRI in awake TRPV1 knockout and wild-type rats.

Front Syst Neurosci · 2015 · PMC4333803 · PMID 25745388

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hedged sentences

0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

a trend toward significanceP < 0.057so close (0.05 < p ≤ 0.1)

The prelimbic cortex showed a trend toward significance ( P < 0.057).

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a statistical trendno p-value reported

Along with the gigantocellular reticular area, which displayed a statistical trend of activation in response to capsaicin in wild-type rats, the parabrachial nucleus has monosynaptic connections to the periaqueductal gray, ventral medial hypothalamus, central nucleus of the amygdala, ventral medial and midline thalamic nuclei (Hylden et al., 1989 ; Bernard et al., 1993 ; Bester et al., 1995 , 1997 ; Jasmin et al., 1997 ; Bourgeais et al., 2001a ).

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