Plasma clusterin as a candidate pre-diagnosis marker of colorectal cancer risk in the Florence cohort of the European Prospective Investigation into Cancer and Nutrition: a pilot study.

BMC Cancer · 2015 · PMC4334607 · PMID 25884309

Europe PMC DOI

hedged sentences

0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

borderline significanceP = 0.057so close (0.05 < p ≤ 0.1)

There was no significant difference between CRC cases and controls though clusterin (CLU) reached a borderline significance (Mann–Whitney U, two-tailed P = 0.057).

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of borderline significanceno p-value reported

Considering the whole EPIC population of our study, targeted proteomics indicated that CLU was the only protein slightly higher in CRC than in controls, but the difference was of borderline significance.

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