An integrative multi-scale analysis of the dynamic DNA methylation landscape in aging.

PLoS Genet · 2015 · PMC4334892 · PMID 25692570

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highly significantno p-value reported

Confirming our hypothesis, we observed a highly significant trend with genes undergoing age-hypermethylation around their TSSs exhibiting significantly lower levels of expression than genes exhibiting age-associated hypomethylation ( Fig. 4A ).

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