Recognition of H3K9 methylation by GLP is required for efficient establishment of H3K9 methylation, rapid target gene repression, and mouse viability.

Genes Dev · 2015 · PMC4335294 · PMID 25637356

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an overall trendno p-value reported

Moreover, even for the rest of the 441 genes that did not cross the twofold threshold, we observed an overall trend of upshift, which suggests that inefficient establishment of H3K9me2 contributed to inefficient silencing of these genes.

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