Barely Significant
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Effect of conjugated linoleic Acid, vitamin e, alone or combined on immunity and inflammatory parameters in adults with active rheumatoid arthritis: a randomized controlled trial.

Int J Prev Med · 2014 · PMC4336987 · PMID 25709792

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borderline significantno p-value reported
Hence in group P increased CCP-A, MMP-3, and IL-1β, but in group E increased IL-1β and CCP-A (borderline significant, lower than placebo group) and in other groups we hadn’t significant increase in those inflammatory parameters.

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