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Long-term donepezil use for dementia with Lewy bodies: results from an open-label extension of Phase III trial.

Alzheimers Res Ther · 2015 · PMC4338564 · PMID 25713600

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an increasing trendno p-value reported
However, this comparison, the present result of mostly mild to moderate severity and the absence of an increasing trend in the incidence over time support a low risk for clinically significant gastrointestinal symptoms.

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