Inducible HSP70 is critical in preventing the aggregation and enhancing the processing of PMP22.

ASN Neuro · 2015 · PMC4342366 · PMID 25694550

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highly significantno p-value reported

While the improvement in the CMT1A samples is only about 10% to 15%, the effect is highly significant and reproducible across independent cultures.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.