Phytochemical analysis and a study on the antiestrogenic antifertility effect of leaves of Piper betel in female albino rat.

Anc Sci Life · 2014 · PMC4342644 · PMID 25737606

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highly significantno p-value reported

The increase in the diestrus index at doses of 1000 and 1500 mg/kg/day was dose-dependent and highly significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.