We found a highly significant increase in nitric oxide release with 100 ng/ml LPS without any further increase with higher (1 μg/ml) LPS concentrations (Additional file 1 : Figure S1A; control: 3.84 ± 0.26 μM; 100 ng/ml: 17.24 ± 0.86 μM; 1 μg/ml: 17.51 ± 0.44 μM; 10 μg/ml: 18.39 ± 0.34 μM; p < 0.05).
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Docosahexaenoic acid (DHA): a modulator of microglia activity and dendritic spine morphology.
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