Preclinical evaluation of cyclin dependent kinase 11 and casein kinase 2 survival kinases as RNA interference targets for triple negative breast cancer therapy.

Breast Cancer Res · 2015 · PMC4344788 · PMID 25837326

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highly significantno p-value reported

Downregulation of CDK11, CK2, or combined CDK11/CK2 protein expression resulted in highly significant loss of cell survival in SUM-149 cells and almost complete loss of cell survival in MDA-MB-231 cells (Figure 4 B).

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