The number of BrdU-labeled cells (/400-fold field of view) was 76.17 ± 8.30, 62.33 ± 8.40, 54.33 ± 7.50, 45.50 ± 6.59, and 28.67 ± 2.73, respectively at 3, 7, 14, 21, and 28 days following hUCB-MSC transplantation, revealing a decreasing trend ( Figure 1 ). hUCB-MSC transplantation ameliorated pathological changes in brain tissues of TBI rats Light microscopy revealed normal cellular structures in rat brains of the sham-surgery group ( Figure 2A ).
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Transplantation of human umbilical cord blood mesenchymal stem cells to treat a rat model of traumatic brain injury.
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