Results Pulmonary and systemic inflammatory markers Intrapulmonary mRNA quantification yielded significantly lower overall expression of COX-2, TNF-α and IL-6 following AP318 inhalation, while the differences in IL-1β and iNOS expressions failed to reach significance (Figures 2 and 3 ).
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Inhalation therapy with the synthetic TIP-like peptide AP318 attenuates pulmonary inflammation in a porcine sepsis model.
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