Plasma leptin concentrations are highly correlated to emotional states throughout the day.

Transl Psychiatry · 2014 · PMC4350520 · PMID 25350298

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highly significantno p-value reported

We found highly significant correlations between fluctuations in plasma leptin concentrations and three psychological variables: sadness, carbohydrate craving and social withdrawal.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.