Optimizing IgG therapy in chronic autoimmune neuropathies: a hypothesis driven approach.

The utility of hand grip strength measurements is also supported by a cross-sectional analysis of 31 CIDP patients using dynamometry, electrophysiology, and conventional clinical assessments, from which Rajabally and Narashimhan reported highly significant correlations between Jamar dynamometer measurements and results of global and upper extremity motor and sensory scores. 107 Ultimately, frequent measurements with hand grip dynamometers or other devices the patient can be instructed to use at home should help determine the proportion of patients who might benefit by weekly or even more frequent IgG dosing, and help to identify the treatment regimens which yield the best long-term results.

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