Indeed, the fractions that inhibited bacteria binding to DCs (Fraction C4, C6, and C8, Figure 4 B), showed strongest DC-SIGN binding in ELISA (Figure 4 C), contained highest levels of MUC1 (Figure 4 D) as well as the highest amount of Lewis x present on MUC1 (Figure 4 E), reflected in a highly significant negative correlation between the percentage of bacteria-positive cells and the levels of MUC1 (Figure 4 F).
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