However, combined inhibition of ROCK and MLCK resulted in almost complete inhibition of coat contraction from the start and led to a highly significant reduction in the rate of actin coat compression at any stage following fusion ( n = 18, Fig. 3G,H ; Fig. 6 ).
← all excerpts
Actin depolymerisation and crosslinking join forces with myosin II to contract actin coats on fused secretory vesicles.
1
—
—