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Impact of ten-valent pneumococcal conjugate vaccination on invasive pneumococcal disease in Finnish children--a population-based study.

PLoS One · 2015 · PMC4364013 · PMID 25781031

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an increasing trendno p-value reported
In addition, an increasing trend in the incidence of non-PCV10 types suggested the development of replacement, although the absolute rates remained low.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.