Inhibition of insulin/IGF-1 receptor signaling protects from mitochondria-mediated kidney failure.

EMBO Mol Med · 2015 · PMC4364945 · PMID 25643582

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highly significantno p-value reported

Phb2 pko mice lacking a functional insulin receptor in podocytes ( Insr pko ) showed a highly significant survival advantage (Fig 4C ).

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