Safe prescribing of non-steroidal anti-inflammatory drugs in patients with osteoarthritis--an expert consensus addressing benefits as well as gastrointestinal and cardiovascular risks.

BMC Med · 2015 · PMC4365808 · PMID 25857826

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a decreasing trendno p-value reported

Over the last 10 years, there has been a decreasing trend in NSAID-induced symptomatic GI events in rheumatic patients [ 39 ] and, in line with that, in hospitalizations due to upper GI complications, while lower GI complications showed an apparent increasing trend [ 40 - 43 ].

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