A highly significant relationship existed between the decrease in CD45RA + CD27 + T cells and increase in the CD45RA + CD27 − T-cell population with either age or CMV response as independent factors (all values of P < 0·0001).
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Multifunctional cytomegalovirus (CMV)-specific CD8(+) T cells are not restricted by telomere-related senescence in young or old adults.
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