Persistence of transmitted HIV-1 drug resistance mutations associated with fitness costs and viral genetic backgrounds.

PLoS Pathog · 2015 · PMC4370492 · PMID 25798934

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highly significantno p-value reported

Thus predicted fitness has a considerable and highly significant impact on reversion rates.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.