Systematic review of the predictive effect of MSI status in colorectal cancer patients undergoing 5FU-based chemotherapy.

BMC Cancer · 2015 · PMC4376504 · PMID 25884995

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a possible trendno p-value reported

This approach could lead to potential bias towards the null hypothesis of no difference, because Figures 3 and 4 show a possible trend with the most significant HRs being the ones with the shortest follow-up time.

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