Consistent with these findings, our univariable analysis demonstrated an inverse correlation (r = -0.186) between the frequencies of CD8+ T cells with low and/or negative CD28 expression (as % of CD8+ T cells) and influenza A/H1N1-specific B cell ELISPOT response at Day 75 that did not quite reach statistical significance (p = 0.06, data not shown).
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The impact of immunosenescence on humoral immune response variation after influenza A/H1N1 vaccination in older subjects.
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