Improvement in plasma drug activity during the early treatment interval among Tanzanian patients with multidrug-resistant tuberculosis.

PLoS One · 2015 · PMC4376785 · PMID 25816161

Europe PMC DOI

hedged sentence

0.0550

closest p · 1.1× alpha

0.0550

boldest claim

The sentences

marginally significantp = 0.055so close (0.05 < p ≤ 0.1)

After adjusting for pre-treatment TTP < 216 hours, either a TDA value > 2-log killing at 4 weeks (OR = 16.84, 95% CI: 1.46–194.58, exact p = 0.02) or an increase in TDA from week 2 to week 4 (OR = 19.33, 95% CI: 1.55–241.51, exact p = 0.023) remained statistical significant, and the total TDA value at 4 weeks was marginally significant (exact p = 0.055).

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