Should kidney donors be genotyped for APOL1 risk alleles?

Kidney Int · 2015 · PMC4382897 · PMID 25826538

Europe PMC DOI

hedged sentence

0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

a statistical trendp=0.057so close (0.05 < p ≤ 0.1)

Kidneys from donors with two APOL1 risk variants (hazard ratio [HR] 3.84; p=0.008) and greater degrees of HLA mismatch (HR 1.52; p=0.03) had shorter allograft survival, with a statistical trend observed for an adverse effect for longer CIT (HR 1.06; p=0.057).

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