The group consisting of swd1 Δ , swd2 Δ , swd3 Δ, set1F H3K4me− , and H3K4R mutants included smaller subsets of differentially expressed probes ( Figure 1C , upper panel), with modestly significant GO enrichment for upregulated transcripts related to stress response and carbohydrate metabolism ( Figure 1—source data 1A ).
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Heterochromatin assembly and transcriptome repression by Set1 in coordination with a class II histone deacetylase.
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