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Evaluation of the esthetic properties of developmental defects of enamel: a spectrophotometric clinical study.

ScientificWorldJournal · 2015 · PMC4385663 · PMID 25874260

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an increasing trendno p-value reported
Epidemiologic data (DDE prevalence in permanent dentition ranges from 10% to 49%) reflect an increasing trend of this condition, which should be considered as a public health problem and a challenge for dental practitioners.

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