Trimethylation of Lys36 on H3 restricts gene expression change during aging and impacts life span.

Genes Dev · 2015 · PMC4387714 · PMID 25838541

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The age-dependent mRNA expression variance shows a strong and highly significant correlation with median gene body H3K36me3 levels (correlation coefficient R 2 of ∼0.7–0.9).

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