Genome-wide methylation profiling of the different stages of hepatitis B virus-related hepatocellular carcinoma development in plasma cell-free DNA reveals potential biomarkers for early detection and high-risk monitoring of hepatocellular carcinoma.

Clin Epigenetics · 2014 · PMC4391300 · PMID 25859288

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

an obvious trendno p-value reported

This represents an obvious trend where CGI-associated DMGs gradually increase along with HCC progression, while CGI-shore-associated DMGs decrease, possibly suggesting that the epigenetic effects that occur during the late stages of HCC development are associated with CGI alone rather than CGI-shores.

also in 1,006 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.