Additive effects of HLA alleles and innate immune genes determine viral outcome in HCV infection.

Gut · 2015 · PMC4392199 · PMID 24996883

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highly significantno p-value reported

In this study, we demonstrate that the Class II alleles (DRB1*01:01 and *04:01) retain their highly significant protective effect, while DQB1*02:01 retains its deleterious effect independently of IFNL3 and KIR2DS3 .

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