Complexities due to single-stranded RNA during antibody detection of genomic rna:dna hybrids.

BMC Res Notes · 2015 · PMC4393563 · PMID 25890199

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borderline significanceno p-value reported

Despite such a large target, we found that the detection of these kilobase R-loops is less than 3-fold above background with borderline significance even with the essential pre-treatment of genomic nucleic acid with RNase A.

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